To be eligible for the B.Sc. degree program at Mannar Thirumalai Naicker College Madurai, candidates must have completed their 10+2 education with a minimum aggregate of 50% in the relevant subjects. Additionally, applicants must have studied Physics, Chemistry, and Biology/Mathematics at the higher secondary level. Admission to the program is based on merit, as determined by the college's admission committee. Candidates may also be required to pass an entrance exam or interview as part of the selection process. It is important for prospective students to carefully review the specific eligibility criteria outlined by the college before applying for the B.Sc. program.