GPAT 2025 Syllabus PDF - Download Latest GPAT Syllabus for All Subjects

Name of Exam

GPAT Exam 2025

Exam Conducting Body

National Testing Agency (NTA)

Duration of Exam

3 hours (180 Minutes)

Syllabus Availability Mode

Online (PDF Format)

Official Website

nta.ac.in

Subjects Included

Pharmaceutical Chemistry, Pharmacology, Biochemistry, etc.

Total Questions Asked

125

Type of Questions

Multiple choice

Questions in Pharmaceutical Chemistry

38 questions

Questions in Pharmaceutics

38 questions

Questions in Pharmacognosy

10 questions

Questions in Pharmacology

28 questions

Questions in Others

11 questions

Minimum Eligibility

Higher secondary with 50% marks in aggregate

Subjects Included

Pharmaceutical Chemistry

Pharmaceutics

Pharmacognosy

Pharmacology

Physical Pharmacy

Organic Chemistry

Dispensing & Hospital Pharmacy

Physical Chemistry

Pharmaceutical Jurisprudence

Pharmaceutical Management

Pharmaceutical Engineering

Human Anatomy and Physiology

Pharmaceutical Analysis

Clinical Pharmacy and Therapeutics

Biochemistry

Biopharmaceutics and Pharmacokinetics

Biotechnology

Pathophysiology

Microbiology

Pharmacology

• Principles of Toxicology

• Neurohumoral Transmission in Autonomic and Central Nervous System

• General Pharmacology

• Vitamins & Minerals

• Drugs Acting on the Respiratory System

• Pharmacology of Peripheral Nervous System

• Chronopharmacology

• Pharmacology of Cardiovascular System

• Immunopharmacology

• Pharmacology of the Central Nervous System

• Pharmacology of Endocrine System

• Neurohumoral Transmission in Autonomic and Central Nervous System

• Vitamins & Minerals

• Chemotherapy

• Autacoids and their Antagonists

• Pharmacology of Drug Acting on the Gastrointestinal Tract

• Principles of Toxicology

• Pharmacology of Peripheral Nervous System

• Drugs Acting on Urinary System

Physical Chemistry

• Composition & Physical States of Matter

• Thermodynamics

• Refractive Index

• Ionic Equilibrium

• Solutions

• Colligative Properties

• Electrochemistry

• Kinetics

Physical Pharmacy

• Micromeritics and Powder Rheology

• Buffer

• Surface and Interfacial Phenomenon

• Solubility

• Matter, Properties of Matter

• Viscosity and Rheology

• Complexation

• Dispersion Systems

Organic Chemistry

• General Principles

• Kinetic & Thermodynamic Control

• Stereochemistry

• Pericyclic Reactions

• Aromaticity & Chemistry of Aromatic Compounds

• Carbohydrates

• Different Classes of Compounds

• Heterocyclic Chemistry

• Amino Acids & Proteins

• Different Aromatic Classes of Compounds

• Polycyclic Aromatic Hydrocarbons

• Stereochemistry

• Carbonyl Chemistry

• Heterocyclic Chemistry

• Protection & Deprotection of Groups

• Different Aromatic Classes of Compounds

• Bridged Rings

• Different Classes of Compounds

• Amino Acids & Proteins

• Protection & Deprotection of Groups

Dispensing and Hospital Pharmacy

• Laboratory Equipment Weighing Methodology

• Indications, Adverse Drug Reactions, Available Dosage Forms, Contraindications, and Packing

• Preparations of Formulations Involving Alcohol Dilution, Allegation, Isotonic Solution

• Labelling Instructions for Dispensed Products

• Reading and Counselling of Prescriptions for Clinical Practice

• Handling of Prescriptions

• Posological Calculations for the Calculation of Infant Dosage

• Study of Current Patent and Proprietary Products, Selected Brand Products and Generic Products

• Enlarging & Reducing Formula Displacement Value

• Compounding and Dispensing Of Prescriptions

Pharmaceutical Chemistry

• Pharmaceutical Inorganic Chemistry

• Pharmaceutical Impurities

• Different Classes of Therapeutic Drugs

• Monographs

• Medicinal Chemistry

• Dentifrices, Desensitizing Agents, & Anticaries Agents

• Various Classes of Therapeutic Agents

• Isotopes

• Therapeutic Classes of Drugs

Pharmaceutical Jurisprudence

• Factory Act

• Drugs and Cosmetics Act 1940, Rules 1945, New Drug applications

• Shops and Establishment Act

• Minimum Wages Act 1948

• Medical Termination of Pregnancy Act 1970

• Psychotropic Substances Act, Narcotic Drugs, and rules thereunder

• Intro to Intellectual Property Rights and Indian Patent Act 1970

• Medical Termination of Pregnancy rules 1975

• Historical Background Drug Legislation in India

• Prevention of Food Adulteration Act (1954)

• Industrial Development and Regulation Act 1951

• Code of Ethics for Pharmacists

• Drugs and Magic Remedies (Objectionable Ads) Act 1954

• An Intro to Standard Institutions and Regulatory Authorities such as BIS,  USFDA, MHRA, ASTM, ISO, TGA, ICH, WHO

• Medicinal and Toilet Preparations Act 1955, Rules 1976

• Prevention of Cruelty to Animals Act 1960

• The Pharmacy Act 1948

• Consumer Protection Act

• Overview of Indian Pharmaceutical Industry

• Drug Price Control Order

Pharmaceutical Management

• Introduction to Management

• Planning and Forecasting

• Standard Institutions and Regulatory Authorities

• World Trade Organization and Trade-Related Intellectual Property Rights

• Inventory Management

• Communication

• Leadership and Motivation

• Human Resource and Development

• Organization

• Gatt

• Research Management

• Marketing Research

Pharmaceutics

• Pharmacy Profession & Introduction To Pharmaceuticals

• Parenteral - Product Requiring Sterile Packaging

• Ophthalmic Preparations

• Introduction to Dosage form

• Suppositories

• Biological Products

• Preformulations

• Pharmaceutical Aerosols

• Packaging Materials

• Cosmetics

• Dosage form Necessities and Additives

• Powders

• Allopathic Dosage Form

• Sources of Drug Information

• Tablets

• Pharmaceutical Plant, Location, Layout

• Suspensions

• Emulsions

• Stability of Formulated Products

• Prolonged Action Pharmaceuticals

• Gmp and Validation

• Semisolids

• Crude Extract

• Novel Drug Delivery System

• Allergenic Extract

• Capsules

• Liquids (Spirits, Aromatic Water, Solutions, Syrups, Elixirs, Liquid For External Uses)

• Pilot Plant Scale-Up Techniques

Pharmaceutical Engineering

• Material of Constructions

• Evaporation

• Drying

• Extraction

• Fluid flow

• Mixing

• Crystallization

• Automated Process Control Systems

• Refrigeration and Air Conditioning

• Distillation

• Size reduction and Size Separation

• Heat Transfer

• Filtration and Centrifugation

• Industrial Hazards & Safety precautions

• Dehumidification and Humidity Control

Pharmacognosy

• Introductory Pharmacognosy

• Classification of Crude Drugs

• Plant Products

• Principles of Plant Classification

• Adulteration and Evaluation of Crude Drugs

• Worldwide Trade of Crude Drugs

• Pharmaceutical Aids

• Toxic Drugs

• Introduction to Phytoconstituents

• Animal Products

• Global Trade of Volatile Oils

• Traditional Herbal Drugs

• Patents

• Biogenetic Pathways

• Ayurvedic System of Medicine

• Enzymes

• Natural Pesticides and Insecticides

• Quantitative Microscopy

• Factors Influencing Quality of Crude Drugs

• Quality Control and Standardization of Herbal Drugs

• Plants Based Industries and Research Institutes in India

• Techniques in Microscopy

• Tannins

• Carbohydrates & Lipids

• Resinous Drugs

• Volatile Oils

• Glycosides

• Homeopathic System of Medicine

• Alkaloids

• Extraction and Isolation Techniques

• Phytopharmaceuticals

• Herbal Formulations

• Herbal Cosmetics

Human Anatomy and Physiology

• Cell Physiology

• Autonomic Nervous System

• Central Nervous System

• Reproductive System

• Skeletal System

• Gastrointestinal Tract

• Respiratory System

• Endocrine Glands

• Cardiovascular System

• Lymphatic System

• The Blood

• Sense Organs

• Urinary System

Pharmaceutical Analysis

• Importance of Quality Control in Pharmacy

• Polarography

• Nephelometry & Turbidimetry

• Chromatography

• Extraction Techniques

• Acid-Base Titrations

• Gravimetry

• Ultraviolet-Visible Spectrometry

• Potentiometry

• Complexometric Titrations

• Calibration

• Mass Spectrometry

• Spectrofluorimetry

• Oxidation-Reduction Titrations

• General Principles of Spectroscopy

• Non-Aqueous Titrations

• Precipitation Titrations

• Proton Nuclear Magnetic Resonance Spectrometry

• Infrared Spectrometry

• Flame Photometry & Atomic Absorption Spectrometry

• Miscellaneous

• Miscellaneous Methods of Analysis

Clinical Pharmacy and Therapeutics

• Drug Information Services 

• Clinical Trials And Types Of Clinical Trials

• Phases Of Clinical Trials

• Drug Interactions

• Therapeutic Drug Monitoring

• Adverse Drug Reaction (Adr)

• Ethical And Regulatory Issues; Good Clinical Practice In Clinical Trials

• Drug Interaction In Pediatric And Geriatric Cases

• Types Of Adr, Mechanism Of Adr.  Monitoring, Drug Interaction, And Reporting Of Adr And Its Importance

• Drug Therapy In Cardiovascular, Gastrointestinal, Hepatic, Renal, And Respiratory Disorders

• Drug Treatment During Menstruation, Pregnancy, And Lactation

• Nutraceuticals, Pharmacovigilance, Therapeutic Drug Monitoring, Essential Drugs And Proper Drug Usage

• General Principles, Maintenance, Preparation In Clinical Pharmacy

• Drug Therapy In Respiratory System Infections, Infective Meningitis, Urinary System Infections, Tb, Hiv, Filaria, And Malaria

• Analysis Of Observational Records In Clinical Pharmacy

• Drug Therapy For Thyroid And Parathyroid Disorders, Menstrual Cycle Disorders, Diabetes Mellitus, Male Sexual Dysfunction And Menopause 

• Drug Therapy For Malignant Disorders Like Lymphoma,Tumors And Leukemia 

• Drug Therapy For Skin And Eye Disorders

• Age-Related Drug Therapy: Drug Therapy For Neonates, Concept Of Posology, Geriatrics And Paediatrics 

• Drug Treatment For Rheumatic Disorders

• Drugs Used In Pregnancy And Lactation 

• Drug Therapy For Psychological And Neurological And Disorders

Biochemistry

• Biological Oxidations & Reductions

• Cell

• Hereditary Diseases

• Lipids

• Nucleic Acids

• Vitamins

• Enzymes

• Carbohydrates

• Proteins

Biopharmaceutics and Pharmacokinetics

• Bio-pharmaceutics

• Bio-availability & Bio-equivalence

• Bio-pharmaceutical Statistics

Biotechnology

• Recombinant DNA Technology

• Plant Cell and Tissue Culture

• Fermentation Technology and Industrial Microbiology

• Biotechnology-Derived Products

• Process and Applications

• Animal Cell Culture

Pathophysiology

• Neoplastic Diseases

• Basic Principles of Cell Injury and Adaptation

• Lab Test for Liver Function

• Immunopathology Including Amyloidosis

• Disorders of Homeostasis: Lymphoid Tissues, White Blood Cells, and Red Blood Cells Related Diseases

• Pathophysiology of Common Diseases

• Lab Tests for Kidney Function Tests

• Disorders of Fluid, Electrolyte and Acid-base Balance

• Infectious Diseases

• Basic Mechanisms of Inflammation and Repair

Microbiology

• Introduction to Microbiology

• Microbial Assay

• Microscopy and Staining Technique

• Biology of Microorganisms

• Microbial Spoilage

• Aseptic Technique

• Vaccines & Sera

• Sterilization & Disinfection

• Fungi and Viruses

Pharmaceutical Analysis

Physical Chemistry

Pharmaceutical Chemistry

Pharmaceutical Engineering

Dispensing and Hospital Pharmacy

Human Anatomy and Physiology

Pathophysiology

Anatomy

Pharmacognosy

Pharmaceutical Jurisprudence

Pharmaceutics

Pharmacology

Biopharmaceutics and Pharmacokinetics

Microbiology

Clinical Pharmacy and Therapeutics

Biotechnology

Pharmaceutics

38

152

Pharmaceutical Chemistry

38

152

Pharmacology

28

112

Pharmacognosy

10

40

Other

11

44

General Pharmacology

Introduction to Pharmacology

 Pharmacodynamics

Pharmacokinetics

Pharmacology of peripheral nervous system

Parasympathomimetics

Parasympatholytics

Sympathomimetics

Sympatholytics

Pharmacology of central nervous system

Psychopharmacological agents

General anesthetics

Narcotic analgesics

Pharmacology of Endocrine system

Hypothalamic and pituitary hormones

Thyroid hormones 

Parathormone

Calcitonin and vitamin-D

Insulin

Autacoids and their Antagonists

Histamine

5-HT and their agonists

Prostaglandins

Thromboxanes

Leukotrienes

Pentagastrin

Principles of toxicology

Definition of poison

Opioids and other addict forming drugs

Study of acute, sub-acute and chronic toxicity 

Different classes of compounds

Alkanes [including cyclic compounds]

Alkenes [including cyclic compounds]

Alkynes [only open-chain compounds]

Aliphatic hydroxyl compounds

Alkyl halides

Aldehydes & Ketones

Different aromatic classes of compounds

Aromatic hydrocarbons

Phenolic compounds

Aromatic & aliphatic amines

Diazonium salts

Carbonyl Chemistry

Mannich condensation/reaction

Robinson annulation

Stobbe condensation

Darzen's glycidic ester synthesis

Beckmann rearrangement

Baeyer Villiger rearrangement

Acid-base titrations

Definitions of normality

Preparation of standard solutions

Law of mass action

Hydrolysis of salts

Strengths of acids & bases

Dissociation constant

Oxidation-reduction titrations

Equivalent weight

Oxalic acid-KMnO4

FeSO4-ceric nitrate

I2-sodium thiosulphate solution titrations

Precipitation titrations

Titrants & indicators used in Mohr's, Volhard's, & Fajan's methods

Calculation of factors in argentometric titrations

Ammonium chloride

Complexometric titrations

Complexing, chelating, & sequestering agents

Standardization of EDTA solution

Use of buffers in EDTA titrations

Gravimetry

Principles of gravimetry

Factors affecting precipitation

Applications of gravimetry in pharmacy

Distribution law

Carbohydrates

Types of carbohydrates

Hexose monophosphate shunt [HMP shunt]

Glycogenesis

Aerobic & anaerobic oxidation

Proteins

Different types of proteins

Denaturation & its effect on biological activity

Urea formation

Transamination & deamination

Lipids

Different types of lipids

Biosynthesis of cholesterol

Ketone bodies

Nucleic acids

Different types of nucleic acids [NAs] 

Different ways of representing DNA

De-novo biosynthesis of NAs

Different types of RNAs 

Biological oxidations & reductions

Oxidation-reduction systems in the body

Oxidative phosphorylation 

Cytochromes & inhibitors 

Plant Cell and Tissue Culture 

Cell and tissue culture Requirements.

Callus culture

Suspension culture

Batch culture.

Animal Cell Culture

Introduction to animal cell culture

Use of FCS, primary culture

Cloning

Fermentation Technology and Industrial Microbiology

Fermentation as a biochemical process

Fermenter - working and construction

Fermentation monitoring

Physical Pharmacy

Matter, properties of matter

Micromeritics and powder rheology

Surface and interfacial phenomenon

Viscosity and rheology

Dispersion systems

Complexation

Pharmaceutics

Pharmaceutical aerosols

Ophthalmic preparations

Stability of formulated products

Prolonged action pharmaceuticals

Novel drug delivery system

GMP and validation

Packaging materials

Pharmacognosy

Quantitative microscopy

Biogenetic pathways

Carbohydrates and lipids

Tannins

Volatile oils

Resinous drugs

Glycosides

Alkaloids

Organic Chemistry

Polycyclic aromatic hydrocarbons

Carbonyl chemistry

Heterocyclic chemistry

Bridged rings

Pharmacology

Pharmacology of the peripheral nervous system

Pharmacology of central nervous system

Pharmacology of the cardiovascular system

Drugs acting on the urinary system

Drugs acting on the respiratory system

Pharmacology of Endocrine System

Matter, properties of matter

States of Matter

Latent Heat and Vapor Pressure

Sublimationcritical point

Relative humidity

Aerosols- Inhalers

Viscosity and rheology

Effect of Temperature

Newtonian Systems

Colloidal Dispersions

Suspensions and Emulsions

Buffer

Buffers in Pharmaceutical Systems

Solvation and Association in Solutions

Solubility of Salts in Water

Dielectric Constant and Solubility

Solubility of Solids in Liquids

Micromeritics and Powder Rheology

Average Particle Size Number 

Sedimentation

Determining Surface Areas

Porosity

Pharmaceutical Inorganic Chemistry

Impurities in Pharmaceutical Substances

Types & Effects of Impurities

Monograph & its Importance

Isotopes- stable & Radioactive

Medicinal Chemistry

Therapeutic Classes of Drugs

General Anesthetics

Local Anesthetics

Diagnostic Agents

Antibiotics

Penicillins

Cephalosporins

Chloramphenicol

Biosynthesis

Adrenergic drugs

Asymmetric Synthesis

Chirality

Enantioselectivity

Enantiomeric

Types of supports & linkers

Introductory Pharmacognosy

Historical Development

Homeopathic

Scope of Pharmacognosy

Classification of Crude Drugs

Organized and Unorganized Drugs

Official and Unofficial drugs

Organized and Unorganized drugs

Principles of Plant Classification

Algae: Rhodophyceae 

Fungi: Ergot Yeast and Penicillium.

Gymnosperm

Pteridophytes

Plant products

Introduction to Plant Bitters

Nutraceuticals

Cosmeceuticals 

Fumigants

Examination Mode

Computer Based Mode

Exam Frequency

Once a Year

Exam Purpose

M.Pharm Admissions in India

Exam Duration

3 Hours/ 180 Minutes

Total Number of Questions

125

Types of Questions Asked

Objective Type/ Multiple Choice Questions (MCQ)

Paper Division

4 Sections

Number of Questions Asked

25 Questions from Each Section

Maximum Marks

500 (125*4)

Validity of GPAT Score Card

3 Years

Pharmacology Test Prep: 1500 USMLE-Style Questions & Answers

Mario Babbini, Mary L. Thomas

Pharmaceutics: The Science of Dosage Form Design

Aulto

Physical Pharmacy

Martin

Trease and Evan’s Pharmacognosy

William Charles Evans

Physical Chemistry Lecture Notes

Prof. Rob Schurko R.W. Schurko, University of Windsor

Instrumental Methods of Chemical Analysis  

B. K. Sarma

Davis’s Pocket Clinical Drug Reference

Cynthia Sanoski & Shamim Tejan

Essential of Medical Pharmacology

K D Tripathi

Modern Technology of Pharmaceutical Analysis

Nirav Son

Text Book of Pharmaceutical Analysis

K. A. Connors

Biochemistry of Lipids, Lipoproteins and Membranes edited

J.E. Vance, Dennis E. Vance

Organic Chemistry

Morrison & Boyd